Lupin III

In Chicago, a sniper kills a man under the orders of the mysterious "Mother". Even more strange, Fujiko seems to be under her spell. Lupin sneaks into Mother's mansion and manages to steal the Dracula Heart ruby. Once every century, this ruby bleeds, and whoever drinks its blood is granted youth for another 100 years. Mother has used the blood to maintain life for the past 300 years and will not be denied. She wants the ruby back, and Fujiko will do anything to reclaim it for her.